🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧪 Experimental Design

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Trial Search

Current Search Criteria:

Intervention: Topotecan and pegylated doxorubicin

Found 27 matching trials

Olaparib Treatment in Relapsed Germline Breast Cancer Susceptibility Gene (BRCA) Mutated Ovarian Cancer Patients Who Have Progressed at Least 6 Months After Last Platinum Treatment and Have Received at Least 2 Prior Platinum Treatments

PHASE3

Comparison of olaparib vs. physician's choice of single agent standard of c...

Status

Completed

Location

Research Site

Start Date

2015-02-06

Trial ID

NCT02282020

Treatments Being Tested

OLAPARIB Single agent chemotherapy

Doxil Topotecan Doublet Cancer Study

PHASE1

The primary objective is to determine the nature and degree of the toxicity...

Status

Completed

Location

Christiana Care Health Services

Start Date

2004-05

Trial ID

NCT00252889

Treatments Being Tested

Topotecan and pegylated doxorubicin

Trial on NIraparib-TSR-042 (Dostarlimab) vs Physician's Choice CHEmotherapy in Recurrent, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment

PHASE3

Randomized phase 3 trial evaluating niraparib plus dostarlimab vs chemother...

Status

Unknown

Location

Azienda Ospedaliera Spedali Civili

Start Date

2020-12-01

Trial ID

NCT04679064

Treatments Being Tested

Niraparib Dostarlimab Pegylated liposomal doxorubicin Paclitaxel Gemcitabine Topotecan Bevacizumab

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer

PHASE3

Drugs used in chemotherapy use different ways to stop tumor cells from divi...

Status

Completed

Location

Gynecologic Oncology Group

Start Date

2001-01

Trial ID

NCT00011986

Treatments Being Tested

Paclitaxel Carboplatin Gemcitabine Hydrochloride Pegylated Liposomal Doxorubicin Hydrochloride Topotecan Hydrochloride Therapeutic Conventional Surgery

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

PHASE2

This phase II trial studies how well Avatar-directed chemotherapy works in ...

Status

Completed

Location

Mayo Clinic in Arizona

Start Date

2015-07-21

Trial ID

NCT02312245

Treatments Being Tested

Bevacizumab Gemcitabine Hydrochloride Paclitaxel Pegylated Liposomal Doxorubicin Hydrochloride Topotecan Hydrochloride

Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer

PHASE2

This randomized phase II/III trial studies how well cediranib maleate and o...

Status

Active Not Recruiting

Location

University of Alabama at Birmingham Cancer Center

Start Date

2016-05-03

Trial ID

NCT02502266

Treatments Being Tested

Cediranib Cediranib Maleate Computed Tomography Magnetic Resonance Imaging Olaparib Paclitaxel Pegylated Liposomal Doxorubicin Hydrochloride Questionnaire Administration Topotecan Topotecan Hydrochloride

Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib

PHASE2

Carcinosarcomas (CS) (malignant mixed Müllerian tumors) are highly aggressi...

Status

Recruiting

Location

ICO Paul Papin

Start Date

2020-07-15

Trial ID

NCT03651206

Treatments Being Tested

Niraparib Niraparib + TSR-042 (Dostarlimab)Chemotherapy Drugs

A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)

PHASE3

This study specifically aims to evaluate how well mocertatug rezetecan (Mo-...

Status

Recruiting

Location

GSK Investigational Site

Start Date

2026-06-18

Trial ID

NCT07286266

Treatments Being Tested

Mocertatug rezetecan Paclitaxel Pegylated liposomal doxorubicin (PLD)Topotecan Gemcitabine Pembrolizumab Bevacizumab

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

PHASE2

This phase II/III trial studies how well trametinib works and compares it t...

Status

Completed

Location

Tennessee Valley Gynecologic Oncology

Start Date

2014-04-11

Trial ID

NCT02101788

Treatments Being Tested

Letrozole Paclitaxel Pegylated Liposomal Doxorubicin Hydrochloride Quality-of-Life Assessment Questionnaire Administration Tamoxifen Citrate Topotecan Trametinib Dimethyl Sulfoxide

Comparing Standard of Care Chemotherapy Treatment to the Combination of Copanlisib and Olaparib for Recurrent Platinum Resistant Ovarian Cancer That Has Progressed Through PARP Inhibitor Therapy

PHASE2

This phase II trial compares copanlisib and olaparib to standard of care ch...

Status

Withdrawn

Location

University of Colorado Hospital

Start Date

2022-06-30

Trial ID

NCT05295589

Treatments Being Tested

Computed Tomography Copanlisib Hydrochloride Magnetic Resonance Imaging Olaparib Paclitaxel Pegylated Liposomal Doxorubicin Hydrochloride Topotecan Hydrochloride

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